Clinical Adult Neurology-xh

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A growing understanding exists of both isolated and combined dystonia as new genes are identified and our knowledge of the phenotypic presentation of previously reported genes has expanded. Genetic testing is commercially available for some of these conditions. Treatment options for dystonia include pharmacologic therapy, chemodenervation, and surgical intervention.

Deep brain stimulation benefits many patients with various types of dystonia. Relationship Disclosure: Dr Shanker reports no disclosure. Fox Foundation and for serving on the editorial board of Movement Disorders. Fox Foundation. Supplemental digital content: Videos accompanying this article are cited in the text as Supplemental Digital Content.


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Localization in Clinical Neurology

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Acta Neuropathol Commun. Irreversible electroporation-induced sciatic neuropathy observed by intraoperative neuromonitoring. Clinimetric testing of the comprehensive cervical dystonia rating scale. Erratum to: The effect of a locally adapted, secondary stroke risk factor self-management program on medication adherence among veterans with stroke. Transl Behav Med. Rapid aspiration screening for suspected stroke: Part 1: Development and validation. Nat Genet. Temporal lobe volume predicts Wada memory test performance in patients with mesial temporal sclerosis.

CNS Spectr. National randomized controlled trial of virtual house calls for people with Parkinson's disease: interest and barriers. Telemed J E Health. Counseling by epileptologists affects contraceptive choices of women with epilepsy. Whole-exome sequencing in familial Parkinson disease. Using medical mannequins to train nurses in stroke swallowing screening. Emergency medical considerations in a space-suited patient.

Ethical considerations for the use of next-generation Alzheimer drugs in symptomatic and at-risk patients. New-onset seizure in adults and adolescents: a review. The international POTS registry: Evaluating the efficacy of an exercise training intervention in a community setting. Heart Rhythm. Sudden unexpected death in epilepsy genetics: Molecular diagnostics and prevention. Development of a patient-reported outcome instrument to assess complex activities of daily living and interpersonal functioning in persons with mild cognitive impairment: The qualitative research phase.

Alzheimers Dement. Application of tauroursodeoxycholic acid for treatment of neurological and non-neurological diseases: Is there a potential for treating traumatic brain injury? Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression.

BMC Neurol. Deleterious rare variants reveal risk for loss of GABAA receptor function in patients with genetic epilepsy and in the general population. Physical activity recommendations for the aging brain: a clinician-patient guide. The epilepsy spectrum: targeting future research challenges. Cold Spring Harb Perspect Med.

Epileptic seizures in Alzheimer disease: a review. Alzheimer Dis Assoc Disord. Effect of deutetrabenazine on chorea among patients with Huntington disease: A randomized clinical trial.

Testing for FXTAS

Quantitative assessment of eye phenotypes for functional genetic studies using Drosophila melanogaster. G3 Bethesda. Dopamine depleters in the treatment of hyperkinetic movement disorders. Expert Opin Pharmacother. Leg stereotypy disorder. Ethical challenges for the medical expert witness. AMA J Ethics. Medical malpractice reform-historical approaches, alternative models, and communication and resolution programs.

Kent TA, Mandava P. Embracing biological and methodological variance in a new approach to pre-clinical stroke testing.

Transl Stroke Res. Racial-ethnic disparities in acute blood pressure after intracerebral hemorrhage. Frequency, risk factors, and outcome of coexistent small vessel disease and intracranial arterial stenosis: results from the stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis SAMMPRIS trial.

Genetics of paediatric hereditary movement disorders

Clinical and genetic features of cervical dystonia in a large multicenter cohort. Development and feasibility testing of a critical care EEG monitoring database for standardized clinical reporting and multicenter collaborative research. The initiator caspase Dronc is subject of enhanced autophagy upon proteasome impairment in Drosophila. Cell Death Differ. Cognitively-related basic activities of daily living impairment greatly increases the risk of death in Alzheimers disease.

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Using the 4 pillars practice transformation program to increase adult influenza vaccination and reduce missed opportunities in a randomized cluster trial. BMC Infect Dis. Neurological and neuropsychiatric adverse effects of dermatologic medications. Lotia M, Jankovic J. Botulinum Toxin for the Treatment of Tremor and Tics.

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New and emerging medical therapies in Parkinson's disease. Binomial regression with a misclassified covariate and outcome. Stat Methods Med Res.

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Shift in interictal relative gamma power as a novel biomarker for drug response in two mouse models of absence epilepsy. Impact of IDH1 mutation status on outcome in clinical trials for recurrent glioblastoma. Newly diagnosed ganglioglioma in an adult patient with multiple sclerosis. Effects of short-term exposure to head-down tilt on cerebral hemodynamics: a prospective evaluation of a spaceflight analog using phase-contrast MRI. Risks and benefits of epilepsy surgery in a pediatric population: Consequences for memory and academic skills.

Crew recovery and contingency planning for a manned stratospheric balloon flight - the StratEx program. Prehosp Disaster Med. KCNQ2 encephalopathy: Features, mutational hot spots, and ezogabine treatment of 11 patients. Impact of cervical dystonia on work productivity: an analysis from a patient registry. Reasons for prolonged length of stay in the epilepsy monitoring unit.

History taking in neurology

Genome-wide association study in essential tremor identifies three new loci. Pure salivatory seizures secondary to a subtle malformation of the right parietal cortex. Neurosci Med. Aicardi syndrome: when to suspect the unexpected. Epileptic Disord. Active search for epileptiform electroencephalogram activity by external stimulation in critically ill patients. Progressive myoclonus epilepsy associated with SACS gene mutations.

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Anterior temporal lobectomy versus selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy. Kleptomania following hypoxic-ischaemic damage to bilateral caudate nuclei. BMJ Case Rep. Meningioangiomatosis: a disease with many radiological faces.

textbook of clinical neurology

Case Rep Neurol Med. Phenytoin-induced isolated chronic, nocturnal dry cough. Epilepsy Behav Case Rep. Hippocampal abnormalities and sudden childhood death.